If your fishing out of a boat there are tons of perch up river in the slips. We pounded them a few days ago on jigging spoons with wax worms. Pretty much non stop action the entire time out. You can also fish inside the breakwall and play with the lake trout.
The South End provides useful resources and discussion forums for those that fish The South End of Lake Michigan for Salmon, Steelhead, Perch, and Bass as well as elsewhere in the Region and Chicago area.